MHB aids liver health improvementModified highland barley regulates lipid metabolism, liver inflammation and gut microbiota in high-fat/cholesterol diet mice as revealed by LC-MS based metabonomics.
Moderately Relevant Study Findings
We explored how modified highland barley (MHB) impacts liver health and gut microbiota in mice on a high-fat diet. Over ten weeks, six groups were fed different diets, with MHB showing significant improvements in liver function and lipid levels compared to those without MHB.
Interestingly, MHB also positively affected gut bacteria diversity and increased levels of beneficial short-chain fatty acids. Our findings suggest that MHB, particularly HB-1, may be a promising dietary option for supporting liver health and managing high lipid levels.
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Barley grass may aid liver healthRegulatory effects of Lactobacillus fermented black barley on intestinal microbiota of NAFLD rats.
Relevant dietary intervention study
We examined how Lactobacillus-fermented black barley impacts rats with nonalcoholic fatty liver disease (NAFLD). Using four different diet groups, we treated some with the fermented barley for 12 weeks. The results showed that this treatment significantly reduced body and liver fat, improved liver function, and enhanced beneficial gut bacteria.
This suggests that fermented black barley could be a promising dietary option to help manage NAFLD and maintain gut health.
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Barley extract protects liver healthChemical composition and hepatoprotective effect of free phenolic extract from barley during malting process.
Hepatoprotective potential of barley
This study focused on examining how free phenolic extracts from barley can protect the liver. We found that administering these extracts to mice significantly reduced markers of liver damage. Additionally, the extracts increased levels of important antioxidant enzymes in the liver.
In lab tests, the extracts also helped protect liver cells from damage and cell death. Overall, our findings suggest that barley grass could serve as a functional food that may effectively aid in preventing liver injury.
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Barley grass shows liver protectionAntioxidant Effect of Barley Sprout Extract via Enhancement of Nuclear Factor-Erythroid 2 Related Factor 2 Activity and Glutathione Synthesis.
Promising but requires more studies.
We explored how barley sprout extract (BSE) can help protect against liver damage caused by alcohol. In our study, we found that BSE not only inhibited harmful oxidative stress but also boosted the activity of important antioxidant pathways in mice.
Specifically, BSE enhanced the activity of a protein called Nrf2, which helps increase glutathione levels—an essential antioxidant. This suggests that barley grass might be a supportive option for liver health, especially in the context of alcohol consumption. Overall, the findings show promise but further research in humans is needed.
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Barley extracts reduce liver fatBarley sprout extracts reduce hepatic lipid accumulation in ethanol-fed mice by activating hepatic AMP-activated protein kinase.
Potential liver disease treatment
We investigated how barley sprout extracts (BSE) impact liver health, particularly in the context of alcohol-induced liver disease. In our studies with mice, those receiving high doses of BSE showed a significant decrease in fat buildup in their livers compared to those on an alcohol-only diet.
Not only did BSE help reduce fat accumulation, but it also activated important pathways related to fat metabolism. This suggests that barley sprout extracts can potentially support liver health by promoting fat breakdown. However, these findings are based on animal studies and require further exploration in humans for validation.
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